Management of neuro-muscular diseases / Myasthenia gravis / ALS

There are more than 400 different neuromuscular diseases both by the importance and the gravity of the muscular attack and its consequences on the organism (orthopedic, respiratory, cardiac, digestive ...) as by their causes (the majority is d genetic origin, some are autoimmune and inflammatory ...). Some appear in newborns or infants: proximal spinal muscular atrophy linked to the SMN1 gene, bulbo-spinal amyotrophies in children, congenital muscular dystrophies, congenital myopathies, congenital myasthenic syndromes, the infantile form of Pompe disease. Others can start in children or adolescents: Duchenne muscular dystrophy, Becker's muscular dystrophy, hypo / hyperkalemic periodic paralysis, Thomsen and Becker congenital myotonias, Eulenburg paramyotonia, McArdle's disease, Emery-Dreifuss muscular dystrophies. Certain neuromuscular diseases generally occur in adults (young or old): facio-scapulo-humeral myopathy, Steinert's myotonic dystrophy, type 2 myotonic dystrophy, Charcot-Marie-Tooth disease, girdle myopathies, distal myopathies, GNE myopathy, myofibrillary myopathies, oculopharyngeal muscular dystrophy. Still others of autoimmune origin appear, some in childhood or adolescence, or others in adulthood (sometimes late): dermatomyositis, necrotizing autoimmune myopathy, autoimmune myasthenia gravis, inclusion myositis.